(AGI) - Washington Oct. 26 - Created in the laboratory the first mouse model of typhoid fever. Research at Columbia University Medical cindy jeffers Center, cindy jeffers published in the journal 'Cell', promises to make great strides in the study of typhus and the creation of new vaccines against this infection remains a major health threats in developing cindy jeffers countries. '"Vaccines are the best solution' practiced to prevent typhus in the Third World. Unfortunately, existing vaccines are only modestly effective cindy jeffers and leave millions of people vulnerable to infection. Our new mouse model of the disease, the first of its type, we have a powerful tool to analyze the disease and to develop better vaccination strategies, "said Sankar Ghosh, one of the authors of the research. Mice and other laboratory animals are resistant to Salmonella typhi, cindy jeffers the bacterium that, through contaminated food and water, spreading the disease. Scientists have discovered the secret of immunity 'of these animals, everything would be in a receptor called TLR11 that, once removed, made the animal sick with typhus. In addition, the researchers also showed that mice could then be immunized against S. typhi thanks to a given vaccine.
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